Malignant melanoma masquerading as an angiofibroma in a patient with MEN-1.

نویسندگان

  • G Thomas Brown
  • Edward W Cowen
  • Chyi-Chia Richard Lee
چکیده

MalignantMelanomaMasquerading as an Angiofibroma in a PatientWithMEN-1 Multiple endocrine neoplasia type 1 (MEN-1) is an autosomal dominant syndrome consisting of endocrine tumors of the parathyroid gland, pituitary gland, and pancreas. MEN-1 is causedby loss of functionmutations in theMEN1 gene,which encodes the tumor suppressor proteinmenin. Cutaneous collagenomas and facial angiofibromas also have been associated with MEN-1 and may serve as diagnostic clues to the diagnosis.Wepresentacaseofamelanoticmelanomaresembling a large angiofibroma in a young man with MEN-1.

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عنوان ژورنال:
  • JAMA dermatology

دوره 151 1  شماره 

صفحات  -

تاریخ انتشار 2015